Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371883 | 0.91 | MITF (0.56) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL15858966 | 0.88 | KDM4E (0.55) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL6215102 | 0.85 | KDM4E (0.68) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL5535883 | 0.84 | NPC1 (0.50) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL2395969 | 0.84 | ALDH1A1 (0.66) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL11407980 | 0.83 | MEN1 (0.65) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL11430874 | 0.82 | ALDH1A1 (0.64) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL4604800 | 0.82 | ALDH1A1 (0.64) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL6601536 | 0.82 | KDM4E (0.64) | KDM4ENPC1RAB9APAX8MEN1 | |
| SCHEMBL5992289 | 0.81 | ALDH1A1 (1.00) | KDM4ENPC1RAB9APAX8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167670-C | Aryl carboxylic acid and tetrazole derivant | - | 2004-09-22 | — | — | CN | disclosed |
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |
| CN-1266054-A | Aryl carboxylic acid and tetrazole derivant | HOFFMANN LA ROCHE (CH) | 2000-09-13 | — | — | CN | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |