SCHEMBL7107619

SCHEMBL7107619

O=C1OC2(OO2)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.53
GOPC Q9HD26 1/20 0.53
LMNA P02545 4/20 0.47
MAPT P10636 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
GPR55 Q9Y2T6 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 1/20 0.47
ESR1 P03372 1/20 0.47
TP53 P04637 1/20 0.47
TYMS P04818 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ESR2 Q92731 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NPSR1 Q6W5P4 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787743 0.76 CFTR (0.57) CFTRGOPCLMNAMAPTTDP1
SCHEMBL3949342 0.74 CFTR (0.73) CFTRGOPCLMNAMAPTTDP1
SCHEMBL11249029 0.74 CFTR (0.55) CFTRGOPCLMNAMAPTTDP1
SCHEMBL30772290 0.74 CFTR (0.73) CFTRGOPCLMNAMAPTTDP1
SCHEMBL32673190 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1
SCHEMBL3505329 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1
SCHEMBL6425661 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1
SCHEMBL31084368 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1
SCHEMBL29672587 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1
SCHEMBL29963323 0.73 CFTR (0.53) CFTRGOPCLMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620892-B1 Increasing fluidity index by cuts of chains using stable nitroxyl free radical compound ATOFINA (FR) 2003-09-16 US claimed
EP-1192192-B1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2003-03-26 EP claimed
JP-2002542346-A 2002-12-10 JP claimed
EP-1192192-A1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN Atofina (FR) 2002-04-03 EP claimed
WO-2000063260-A1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2000-10-26 WO claimed
US-3956253-A PEROXIDE CROSSLINKING AGENT, COMPRESSION, PLASTICIZING RUHRCHEMIE AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-6620892-B1 Increasing fluidity index by cuts of chains using stable nitroxyl free radical compound ATOFINA (FR) 2003-09-16 US disclosed
EP-1192192-B1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2003-03-26 EP disclosed
EP-1192192-A1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN Atofina (FR) 2002-04-03 EP disclosed
WO-2002024767-A1 PEROXIDE DEGRADATION OF POLYMERS IN THE PRESENCE OF MULTIFUNCTIONAL STABLE FREE RADICALS ATOFINA (FR) 2002-03-28 WO disclosed
WO-2000063260-A1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2000-10-26 WO disclosed
US-3956253-A PEROXIDE CROSSLINKING AGENT, COMPRESSION, PLASTICIZING RUHRCHEMIE AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed