SCHEMBL3949342

SCHEMBL3949342

O=C1OC2(c3ccccc31)c1ccccc1-c1ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.73
GOPC Q9HD26 1/20 0.73
MAPT P10636 6/20 0.63
LMNA P02545 6/20 0.63
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
TDP1 Q9NUW8 4/20 0.63
POLB P06746 3/20 0.63
CYP3A4 P08684 3/20 0.63
GPR55 Q9Y2T6 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
TP53 P04637 2/20 0.63
ALOX15 P16050 2/20 0.63
ALDH1A1 P00352 2/20 0.63
ESR1 P03372 1/20 0.63
TYMS P04818 1/20 0.63
TSHR P16473 1/20 0.63
ESR2 Q92731 1/20 0.63
HSD17B10 Q99714 1/20 0.63
NPSR1 Q6W5P4 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772290 1.00 CFTR (0.73) CFTRGOPCMAPTLMNAMEN1
SCHEMBL29486497 0.86 MAPT (0.69) CFTRGOPCMAPTLMNAMEN1
SCHEMBL30004394 0.86 MAPT (0.69) CFTRGOPCMAPTLMNAMEN1
SCHEMBL10533116 0.86 CFTR (0.61) CFTRGOPCMAPTLMNAMEN1
SCHEMBL6916063 0.86 LMNA (0.69) CFTRGOPCMAPTLMNAMEN1
SCHEMBL29474194 0.86 MAPT (0.69) CFTRGOPCMAPTLMNAMEN1
SCHEMBL8156691 0.86 POLB (0.64) CFTRGOPCMAPTLMNAMEN1
SCHEMBL77954 0.86 MAPT (0.69) CFTRGOPCMAPTLMNAMEN1
SCHEMBL6526046 0.86 GNG2 (0.64) CFTRGOPCMAPTLMNAMEN1
SCHEMBL17105828 0.86 CFTR (0.61) CFTRGOPCMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083262-A1 THERMAL RECORDING MATERIALS APPVION, INC. (US) 2016-10-26 EP disclosed
EP-2014735-A2 POLYMER ANISOTROPIC ELECTROCONDUCTIVE GLUING MATERIAL AND A GLUING METHOD Koltsova, Anastasia Adrianovna (RU) 2009-01-14 EP disclosed
WO-2007107524-A1 PRESSURE-ACTUABLE SWITCHING DEVICE AND ASSOCIATED PRESSURE SENSOR IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-27 WO disclosed
WO-2007107522-A1 DEVICES WITH A PRESSURE-SENSITIVE LAYER COMPRISING INTRINSICALLY PRESSURE-SENSITIVE ORGANIC MATERIAL IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-27 WO disclosed
WO-2007107523-A1 PRESSURE SENSOR FOR MEASURING A CHARACTERISTIC OF A PRESSURE APPLIED TO THE SENSOR IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-27 WO disclosed
WO-2007107525-A1 PRESSURE SENSOR IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-27 WO disclosed
EP-1835272-A1 Pressure sensor IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-19 EP disclosed
EP-1835271-A1 Pressure-actuatable switching device and associated pressure sensor IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. (LU) 2007-09-19 EP disclosed
EP-0124377-B1 CHROMOGENIC COMPOUNDS YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) 1991-09-25 EP disclosed
EP-0124377-A2 Chromogenic compounds YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) 1984-11-07 EP disclosed