SCHEMBL11249029

SCHEMBL11249029

NC1(N)OC(=O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.55
GOPC Q9HD26 1/20 0.55
POLB P06746 3/20 0.53
LMNA P02545 4/20 0.48
MAPT P10636 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
GPR55 Q9Y2T6 2/20 0.48
CYP3A4 P08684 2/20 0.48
ALOX15 P16050 2/20 0.48
ALDH1A1 P00352 1/20 0.48
ESR1 P03372 1/20 0.48
TP53 P04637 1/20 0.48
TYMS P04818 1/20 0.48
TSHR P16473 1/20 0.48
ESR2 Q92731 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPSR1 Q6W5P4 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787743 0.78 CFTR (0.57) CFTRGOPCPOLBLMNAMAPT
SCHEMBL2334036 0.77 CFTR (0.61) CFTRGOPCPOLBLMNAMAPT
SCHEMBL3949342 0.76 CFTR (0.73) CFTRGOPCPOLBLMNAMAPT
SCHEMBL30772290 0.76 CFTR (0.73) CFTRGOPCPOLBLMNAMAPT
SCHEMBL11289852 0.76 CFTR (0.46) CFTRGOPCPOLBLMNAMAPT
SCHEMBL15169316 0.76 CFTR (0.46) CFTRGOPCPOLBLMNAMAPT
SCHEMBL15263629 0.76 CFTR (0.46) CFTRGOPCPOLBLMNAMAPT
SCHEMBL11288549 0.76 CFTR (0.50) CFTRGOPCPOLBLMNAMAPT
SCHEMBL6425661 0.74 CFTR (0.53) CFTRGOPCPOLBLMNAMAPT
SCHEMBL7107619 0.74 CFTR (0.53) CFTRGOPCPOLBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003726-B1 SUBSTITUTED DIAMINOPHTHALIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COLOUR FORMERS IN PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY AG (CH) 1982-01-20 EP claimed
EP-0003726-A1 Substituted diaminophthalides, process for their preparation and their use as colour formers in pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1979-09-05 EP claimed
EP-2742031-B1 METHOD FOR PRODUCING BENZOXAZINE COMPOUNDS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2017-02-22 EP disclosed
EP-0003726-B1 SUBSTITUTED DIAMINOPHTHALIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COLOUR FORMERS IN PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY AG (CH) 1982-01-20 EP disclosed
EP-0003726-B1 SUBSTITUTED DIAMINOPHTHALIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COLOUR FORMERS IN PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY AG (CH) 1982-01-20 EP disclosed
US-4291902-A PRESSURE- AND HEAT-SENSITIVE ELEMENTS; COPYING; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1981-09-29 US disclosed
US-4191690-A COLOR FORMERS CIBA-GEIGY CORPORATION (US) 1980-03-04 US disclosed
EP-0003726-A1 Substituted diaminophthalides, process for their preparation and their use as colour formers in pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1979-09-05 EP disclosed
EP-0003726-A1 Substituted diaminophthalides, process for their preparation and their use as colour formers in pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1979-09-05 EP disclosed
EP-0003726-A1 Substituted diaminophthalides, process for their preparation and their use as colour formers in pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1979-09-05 EP disclosed