Methane

Methane

SCHEMBL7107717

C.CCc1nccn1CCC#N

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPG P10696 2/20 0.38
TLR8 Q9NR97 2/20 0.38
PLAA Q9Y263 1/20 0.38
CSNK2A1 P68400 1/20 0.37
ALPL P05186 1/20 0.37
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
KCNH2 Q12809 3/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 3/20 0.36
POLB P06746 1/20 0.36
CDK1 P06493 1/20 0.34
KDR P35968 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HIF1A Q16665 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3420916 0.98 TLR8 (0.39) ALPGTLR8PLAACSNK2A1ALPL
SCHEMBL718394 0.85 KCNH2 (0.39) TLR8CSNK2A1KCNH2PDE4APDE4B
SCHEMBL10824697 0.81 TLR8 (0.44) TLR8CSNK2A1KCNH2PDE4APDE4B
SCHEMBL27899857 0.81 CSNK2A1 (0.38) CSNK2A1KCNH2PDE4APDE4BPDE4C
SCHEMBL31519798 0.80 ALPG (0.40) ALPGTLR8PLAACSNK2A1ALPL
SCHEMBL31519797 0.80 ALPG (0.40) ALPGTLR8PLAACSNK2A1ALPL
SCHEMBL9231229 0.80 TLR8 (0.43) TLR8CSNK2A1KCNH2PDE4APDE4B
SCHEMBL27857586 0.80 TLR8 (0.43) TLR8CSNK2A1KCNH2PDE4APDE4B
SCHEMBL83434 0.80 TLR8 (0.43) TLR8CSNK2A1KCNH2PDE4APDE4B
SCHEMBL30438581 0.78 ALPG (0.44) ALPGPLAAALPLALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642416-B1 FIBER/RESIN COMPOSITES AND METHOD OF PREPARATION LOCTITE CORP (US) 2003-10-01 EP claimed