SCHEMBL718394

SCHEMBL718394

CCCc1nccn1CCC#N

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
TLR8 Q9NR97 2/20 0.37
CSNK2A1 P68400 1/20 0.36
JAK1 P23458 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824697 0.89 TLR8 (0.44) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL83434 0.88 TLR8 (0.43) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL9231229 0.88 TLR8 (0.43) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL27857586 0.88 TLR8 (0.43) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL3420916 0.86 TLR8 (0.39) KCNH2ALDH1A1POLBKMT2APDE4A
Methane SCHEMBL7107717 0.85 ALPG (0.38) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL4227889 0.82 ALDH1A1 (0.46) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL27899857 0.79 CSNK2A1 (0.38) KCNH2ALDH1A1POLBKMT2APDE4A
SCHEMBL4361611 0.79 ALDH1A1 (0.61) KCNH2ALDH1A1POLBKMT2ATLR8
SCHEMBL16061241 0.78 CSNK2A1 (0.42) KCNH2ALDH1A1POLBKMT2ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526306-B1 PHOTOCHROMIC ARTICLE SDC TECH INC (US) 2025-02-26 EP disclosed
CN-114040950-B Composition for forming hard coating layer of resin base material and laminate using same 日本精化株式会社 2023-06-02 CN disclosed
CN-110431213-B Photochromic articles SDC 科技有限公司 2023-05-09 CN disclosed
US-20220380562-A1 COMPOSITION FOR FORMING HARD COAT OF RESIN SUBSTRATE AND LAMINATE USING THE SAME NIPPON FINE CHEMICAL CO., LTD. (JP) 2022-12-01 US disclosed
CN-114040950-A Composition for forming hard coat layer on resin substrate and laminate using same 日本精化株式会社 2022-02-11 CN disclosed
US-11168223-B2 Photochromic article SDC TECHNOLOGIES, INC. (US) 2021-11-09 US disclosed
WO-2020255958-A1 COMPOSITION FOR FORMING HARD COAT FOR RESIN BASE MATERIAL, AND MULTILAYER BODY USING SAME 日本精化株式会社 2020-12-24 WO disclosed
EP-3080184-B1 COATING COMPOSITIONS COMPRISING A BLOCKED ISOCYANATE SILANE SDC TECH INC (US) 2020-09-30 EP disclosed
EP-1894988-B1 Tetraoxy-silane lubricating oil compositions CHEVRON ORONITE CO (US) 2020-04-15 EP disclosed
US-20190092950-A1 PHOTOCHROMIC ARTICLE SDC TECHNOLOGIES, INC. 2019-03-28 US disclosed
EP-0526975-B1 Coating composition for optical plastic moldings ITOH OPTICAL IND (JP) 1995-07-26 EP disclosed
EP-0407174-B1 Highly tintable abrasion resistant coatings PILKINGTON AEROSPACE INC (US) 1994-10-12 EP disclosed
US-5322888-A Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0526975-A2 Coating composition for optical plastic moldings ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1993-02-10 EP disclosed
EP-0486196-A2 Highly tintable abrasion resistant coatings SWEDLOW, INC. (US) 1992-05-20 EP disclosed
US-5102695-A Blend of colloidal silica, polysiloxane and alkylated amine formaldehyde compound SWEDLOW, INC. (US) 1992-04-07 US disclosed
US-5013608-A Polysilsesquioxanes, coatings for eyeglasses, windows, ultraviolet radiation protection SWEDLOW, INC. (US) 1991-05-07 US disclosed
EP-0407174-A2 Highly tintable abrasion resistant coatings Pilkington Aerospace Inc. (US) 1991-01-09 EP disclosed
US-4355135-A SILOXANE, SILICA COATING RESINS DOW CORNING CORPORATION (US) 1982-10-19 US disclosed
US-4294950-A POLYVALENT CARBOXYLIC ACID BONDED THERETO ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1981-10-13 US disclosed