Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 14/20 | 0.56 |
| ▸ | HTR3A | P46098 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793974 | 0.87 | HTR3A (0.58) | HTR4HTR3AKCNH2 | |
| SCHEMBL17176553 | 0.84 | HTR3A (0.59) | HTR4HTR3AKCNH2 | |
| SCHEMBL17170659 | 0.83 | HTR3A (0.57) | HTR4HTR3AKCNH2 | |
| SCHEMBL3157359 | 0.83 | HTR3A (0.64) | HTR4HTR3AKCNH2 | |
| SCHEMBL17170656 | 0.81 | HTR3A (0.59) | HTR4HTR3AKCNH2 | |
| SCHEMBL19068179 | 0.81 | HTR3A (0.56) | HTR4HTR3AKCNH2 | |
| SCHEMBL7109471 | 0.79 | HTR3A (0.43) | HTR4HTR3AKCNH2 | |
| SCHEMBL17176581 | 0.79 | HTR3A (0.57) | HTR4HTR3AKCNH2 | |
| SCHEMBL7372160 | 0.78 | HTR4 (0.47) | HTR4HTR3AKCNH2 | |
| SCHEMBL8113954 | 0.78 | HTR3A (0.47) | HTR4HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097136-B1 | PROCESS FOR THE PREPARATION OF AN INDOLE DERIVATIVE | SMITHKLINE BEECHAM PLC (GB) | 2003-10-22 | — | — | EP | claimed |
| EP-0922048-B1 | PROCESS FOR THE PREPARATION OF N- (1-n-BUTYL-4-PIPERIDINYL)METHYL] -3,4-DIHYDRO -2H-[1,3] OXAZINO[3,2-a] INDOLE-10-CARBOXAMIDE AND SALTS AND INTERMEDIATES IN THE PROCESS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | claimed |