SCHEMBL7107816

SCHEMBL7107816

CC1CCCC(c2ccccc2O)(c2ccccc2O)C1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
ALOX12 P18054 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
TRPA1 O75762 1/20 0.36
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531177 0.78 ALDH1A1 (0.42) ALDH1A1KDM4EMAPTALOX12TDP1
SCHEMBL8064834 0.78 ALDH1A1 (0.42) ALDH1A1KDM4EMAPTALOX12TDP1
SCHEMBL16581443 0.77 MEN1 (0.39) MAPTOPRM1OPRD1OPRK1TRPA1
SCHEMBL9858405 0.77
SCHEMBL22811872 0.76 ESR1 (0.50) ALDH1A1KDM4EGAAMAPTALOX12
SCHEMBL10513090 0.75 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTTDP1OPRM1
SCHEMBL29415365 0.75 ESR1 (0.44) ALDH1A1KDM4EMAPTTDP1HPGD
SCHEMBL444739 0.75 ESR1 (0.44) ALDH1A1KDM4EMAPTTDP1HPGD
SCHEMBL1056667 0.75 ESR1 (0.57) ALDH1A1KDM4EGAAMAPTALOX12
SCHEMBL935956 0.74 ESR2 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1203043-B1 OLIGOMERIC BISCHLOROCARBONIC ACID ESTERS OBTAINED FROM SELECTED CYCLOALIPHATIC BISPHENOLS AND OTHER BISPHENOLS BAYER AG (DE) 2003-10-08 EP disclosed
US-6590058-B1 Polycarbonates from mixtures of carbocyclic phenolic alcohols-2+, used as substrates having heat resistance BAYER AKTIENGESELLSCHAFT (DE) 2003-07-08 US disclosed
US-5269887-A Removing phenol from bisphenol adduct by distillation or sublimation BAYER AKTIENGESELLSCHAFT (DE) 1993-12-14 US disclosed