SCHEMBL444739

SCHEMBL444739

Oc1ccccc1C1(c2ccccc2O)CCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 2/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
CA2 P00918 1/20 0.43
LMNA P02545 1/20 0.43
FYN P06241 1/20 0.43
POLB P06746 1/20 0.43
CA3 P07451 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
MMP9 P14780 1/20 0.43
HPGD P15428 1/20 0.43
NFKB1 P19838 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415365 1.00 ESR1 (0.44) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL2640042 0.98 ESR1 (0.46) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL9838331 0.98 ESR1 (0.43) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL379394 0.98 ESR1 (0.46) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL31490381 0.98 ESR1 (0.46) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL10513090 0.95 ALDH1A1 (0.43) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL10514967 0.90 ALDH1A1 (0.47) ALDH1A1ALOX15KDM4ENPC1CA12
SCHEMBL9327102 0.90 ALDH1A1 (0.47) ALDH1A1ALOX15KDM4ENPC1CA12
SCHEMBL4552622 0.85 ESR1 (0.50) ESR1ESR2ALDH1A1L3MBTL1AKR1C1
SCHEMBL8840942 0.82 ALDH1A1 (0.44) ESR1ESR2ALDH1A1ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 907 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340738-B2 ESTER INTERCHANGE; CRYSTALLIZATION GENERAL ELECTRIC COMPANY 2002-01-22 US claimed
US-6294642-B1 TRANSESTERIFYING A DIHYDROXY COMPOUND AND CARBONIC DIESTER TO FORM THE POLYCARBONATE GENERAL ELECTRIC COMPANY 2001-09-25 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-12577391-B2 Chemically-resistant flame retardant compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-17 US disclosed
US-20260042914-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECH BV (NL) 2026-02-12 US disclosed
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2026-01-01 US disclosed
US-12473474-B2 Addition curable silicone adhesive compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2025-11-18 US disclosed
US-20250320358-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2025-10-16 US disclosed
US-12435218-B2 Polycarbonate compositions having improved chemical resistance, articles formed thereof, and methods of manufacture SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-10-07 US disclosed
US-20250289953-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-09-18 US disclosed
US-20250282087-A1 METHOD FOR PRODUCING AN OPTICAL ELEMENT FROM PLASTIC DOCTER OPTICS SE (DE) 2025-09-11 US disclosed
US-5418315-A Melt polymerization of hydroquinone and a bisphenol, catalyst of alkali metal compound, chemical resistance and good hue GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5371170-A Stabilizing the condensation polymerization of polycarbonates in presence of an alkali metal or alkaline earth metal compound and a sulfonic acid compound or/and an epoxy compound GE PLASTICS JAPAN (JP) 1994-12-06 US disclosed
US-5324809-A Melt catalytic preparation of copolymeric polycarbonate from hydroquinone GE PLASTICS JAPAN, LTD. (JP) 1994-06-28 US disclosed
US-5306801-A Heat resistance, hue stability, water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-04-26 US disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520805-A2 Polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520804-A2 Copolymeric polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0331095-A1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORPORATION (US) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577391-B2 Chemically-resistant flame retardant compositions RPL3, RPL4, UFM1 ESR1 1778/4885ESR2 1707/4885ALDH1A1 1378/4885
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA ESR1 275/4885ESR2 344/4885ALDH1A1 3743/4885
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF LCP1, COL2A1, SHBG ESR1 11/4885ESR2 38/4885ALDH1A1 2100/4885
US-20260042914-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM PBRM1, LAGE3, RPTOR ESR1 391/4885ESR2 682/4885ALDH1A1 3234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.