Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7106717 | 0.83 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL7104311 | 0.83 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL7101678 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6445780 | 0.81 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL7104037 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7102921 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7108943 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7105826 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7107272 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7106034 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856518-B1 | Metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA SA (ES) | 2003-04-09 | — | — | EP | disclosed |
| US-6018064-A | Metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 2000-01-25 | — | — | US | disclosed |
| EP-0856518-A1 | Metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 1998-08-05 | — | — | EP | disclosed |