Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108299 | 1.00 | KDM5A (0.32) | KDM5AKDM4CKDM5BESR2PANK3 | |
| SCHEMBL7027965 | 0.91 | RORC (0.32) | KDM5AKDM4CKDM5BESR2PANK3 | |
| SCHEMBL7027963 | 0.88 | KDM5A (0.34) | KDM5AKDM4CKDM5BESR2PANK3 | |
| SCHEMBL12228201 | 0.79 | — | — | |
| SCHEMBL15420175 | 0.79 | — | — | |
| SCHEMBL15778154 | 0.79 | PANK3 (0.41) | KDM5AKDM4CKDM5BESR2PANK3 | |
| SCHEMBL730073 | 0.77 | GPR119 (0.33) | ESR2 | |
| SCHEMBL8972126 | 0.76 | HTR2A (0.36) | ESR2 | |
| SCHEMBL8038495 | 0.76 | CYP17A1 (0.34) | — | |
| SCHEMBL7107932 | 0.75 | CYP2C9 (0.46) | KDM5AKDM4CKDM5BESR2PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |