SCHEMBL7108403

SCHEMBL7108403

COC(=O)C(C(=O)OC)C(CC(=O)c1ccccc1)c1ccc(OC)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.68
KMT2A Q03164 4/20 0.57
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TDP1 Q9NUW8 1/20 0.57
MAPT P10636 3/20 0.53
LMNA P02545 2/20 0.53
MGAM O43451 1/20 0.52
GAA P10253 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
PLA2G1B P04054 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
NPSR1 Q6W5P4 2/20 0.48
PAX8 Q06710 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
CNR2 P34972 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448370 0.90 KMT2A (0.66) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL7109702 0.90 KMT2A (0.66) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL2138586 0.89 L3MBTL1 (0.71) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL7111978 0.87 KMT2A (0.59) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL2140616 0.83 PDPK1 (0.67) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL29041179 0.81 KMT2A (0.82) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL658330 0.81 PDPK1 (0.72) L3MBTL1KMT2ANPC1NPSR1POLB
SCHEMBL26820557 0.80 L3MBTL1 (0.75) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL26820571 0.80 L3MBTL1 (0.75) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL13239389 0.79 KMT2A (0.53) L3MBTL1KMT2AALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352687-A1 Preparation of new layered double hydroxides exchanged with diisopropylamide for c-c bond forming reaction Council of Scientific and Industrial Research (IN) 2003-10-15 EP disclosed