Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448370 | 0.91 | KMT2A (0.66) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL7109702 | 0.91 | KMT2A (0.66) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL7108403 | 0.87 | L3MBTL1 (0.68) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL658330 | 0.82 | PDPK1 (0.72) | KMT2AL3MBTL1NPC1MEN1PDPK1 | |
| SCHEMBL7109210 | 0.81 | KMT2A (0.67) | KMT2AL3MBTL1NPC1MEN1ALDH1A1 | |
| SCHEMBL29041217 | 0.81 | KMT2A (0.84) | KMT2AL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL10252711 | 0.79 | PDPK1 (0.72) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL820802 | 0.78 | KMT2A (0.64) | KMT2AL3MBTL1NPC1MEN1ALDH1A1 | |
| SCHEMBL13239389 | 0.77 | KMT2A (0.53) | KMT2AL3MBTL1MEN1ALDH1A1PDPK1 | |
| SCHEMBL17767262 | 0.77 | NPC1 (0.54) | KMT2AL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352687-A1 | Preparation of new layered double hydroxides exchanged with diisopropylamide for c-c bond forming reaction | Council of Scientific and Industrial Research (IN) | 2003-10-15 | — | — | EP | disclosed |