Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143990 | 0.64 | — | — | |
| SCHEMBL8974366 | 0.64 | — | — | |
| SCHEMBL3452328 | 0.60 | — | — | |
| SCHEMBL1649841 | 0.60 | — | — | |
| SCHEMBL18936093 | 0.58 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL133762 | 0.58 | — | — | |
| SCHEMBL796920 | 0.58 | MAPT (0.58) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL13092058 | 0.58 | — | — | |
| SCHEMBL12217614 | 0.57 | MAOB (0.44) | KMT2AKDM4ELMNACYP1A2POLB | |
| SCHEMBL2145668 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927730-B1 | Photochromic Polyurethanes | BAYER AG (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0889084-B1 | Photochromic compositions having improved fade rate | BAYER AG (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6166129-A | Photochromic polyurethanes | BAYER CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-6107395-A | A PHOTOCHROMIC DYE SELECTED FROM THE GROUP CONSISTING OF SPIROOXAZINES, FULGIDES, FULGIMIDES, AND NAPHTHOPYRANS AND RADIATION TRANSPARENT MATRIX OF POLYURETHANE OF AN ALIPHATIC DIISOCYANATE AND POLYOLS; HIGH-SPEED ?COLORED? STATE CHANGE | BAYER CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| US-6065836-A | AROMATIC POLYCARBONATE AND POLYCAPROLACTONE BLEND; INSERT MOLDING | BAYER CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| EP-0927730-A1 | Photochromic Polyurethanes | Bayer Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0889084-A1 | Photochromic compositions having improved fade rate | Bayer Corporation (US) | 1999-01-07 | — | — | EP | disclosed |
| US-5552090-A | Photochromic naphthopyran compounds | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |