SCHEMBL8974366

SCHEMBL8974366

Nc1[c]ccc2cc[c]c(O)c12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019186 0.77 JAK2 (0.39)
SCHEMBL972274 0.71 ALDH1A1 (0.45)
SCHEMBL29212679 0.70 MEN1 (0.44)
SCHEMBL7068249 0.64 NT5E (0.57)
SCHEMBL7108438 0.64 MEN1 (0.31)
SCHEMBL6470192 0.64
SCHEMBL4895507 0.64
SCHEMBL6633176 0.63 TTR (0.50)
SCHEMBL9621428 0.62 CYP1A2 (0.33)
SCHEMBL2145668 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5488101-A DYES WITH NAPHTHOL GROUPS FOR IMAGES AND FIBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-01-30 US claimed
EP-0040806-B1 WATER-SOLUBLE, COLOURED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-19 EP claimed
US-4649193-A COTTON, WOOL, POLYAMIDES; COLOR-AND WASH FASTNESS HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-10 US disclosed