SCHEMBL7108442

SCHEMBL7108442

OC(O)c1cc2c[c]ccc2o1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11669055 0.76
SCHEMBL767149 0.72 DYRK1A (0.41)
SCHEMBL4477930 0.72 CDK9 (0.41)
SCHEMBL3929855 0.72
SCHEMBL5396026 0.72 HDAC6 (0.41)
SCHEMBL7038519 0.70 FLT3 (0.42)
SCHEMBL3483330 0.70 PIM1 (0.53)
SCHEMBL15515840 0.69 CYP2A6 (0.58)
SCHEMBL3488474 0.69 ALDH1A1 (0.56)
SCHEMBL16720104 0.68 GSK3B (0.41) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927730-B1 Photochromic Polyurethanes BAYER AG (US) 2003-09-17 EP disclosed
EP-0889084-B1 Photochromic compositions having improved fade rate BAYER AG (US) 2001-03-14 EP disclosed
US-6166129-A Photochromic polyurethanes BAYER CORPORATION (US) 2000-12-26 US disclosed
US-6107395-A A PHOTOCHROMIC DYE SELECTED FROM THE GROUP CONSISTING OF SPIROOXAZINES, FULGIDES, FULGIMIDES, AND NAPHTHOPYRANS AND RADIATION TRANSPARENT MATRIX OF POLYURETHANE OF AN ALIPHATIC DIISOCYANATE AND POLYOLS; HIGH-SPEED ?COLORED? STATE CHANGE BAYER CORPORATION (US) 2000-08-22 US disclosed
US-6065836-A AROMATIC POLYCARBONATE AND POLYCAPROLACTONE BLEND; INSERT MOLDING BAYER CORPORATION (US) 2000-05-23 US disclosed
EP-0927730-A1 Photochromic Polyurethanes Bayer Corporation (US) 1999-07-07 EP disclosed
EP-0889084-A1 Photochromic compositions having improved fade rate Bayer Corporation (US) 1999-01-07 EP disclosed
US-5552090-A Photochromic naphthopyran compounds PPG INDUSTRIES, INC. (US) 1996-09-03 US disclosed