Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6864729 | 0.70 | L3MBTL1 (0.33) | L3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL7108556 | 0.68 | L3MBTL1 (0.34) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL7108557 | 0.66 | L3MBTL1 (0.34) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL6698527 | 0.63 | KMT2A (0.31) | — | |
| Hydrochloric Acid SCHEMBL6850658 | 0.61 | L3MBTL1 (0.32) | L3MBTL1POLB | |
| SCHEMBL9764653 | 0.59 | L3MBTL1 (0.57) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3958491 | 0.59 | L3MBTL1 (0.57) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2737240 | 0.58 | L3MBTL1 (0.55) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20743821 | 0.57 | L3MBTL1 (0.53) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3217546 | 0.57 | L3MBTL1 (0.53) | L3MBTL1POLBGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |