Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645851 | 0.71 | GPR84 (0.57) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL28692972 | 0.70 | GPR84 (0.66) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL2087167 | 0.69 | MAPT (0.66) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL31642403 | 0.68 | KMT2A (0.53) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL31642219 | 0.68 | KMT2A (0.53) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL31642357 | 0.68 | KMT2A (0.53) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL31646013 | 0.68 | KMT2A (0.53) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL31642547 | 0.68 | KMT2A (0.53) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL7108667 | 0.68 | MEN1 (0.41) | MEN1KMT2AMAPTHTR2AHTR2C | |
| SCHEMBL273410 | 0.67 | HTR2A (0.58) | MGAMGAASIMGAM2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019434-B1 | INHIBITORS OF METALLOPROTEINASES, THEIR THERAPEUTIC USE, AND PROCESS FOR THE PRODUCTION OF THE STARTING COMPOUND IN THEIR SYNTHESIS | POLIFARMA SPA (IT) | 2003-10-01 | — | — | EP | disclosed |