Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312775 | 0.72 | SLC6A2 (0.47) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL2944736 | 0.69 | SLC6A2 (0.47) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL28686176 | 0.69 | MEN1 (0.49) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL8528014 | 0.68 | SMN1; SMN2 (0.40) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL8001498 | 0.68 | SLC6A2 (0.45) | MEN1KMT2AKDM4EMAPTSLC6A2 | |
| SCHEMBL7108666 | 0.68 | MGAM (0.42) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL9551961 | 0.67 | MEN1 (0.43) | MEN1KMT2ALMNAMPOMAPT | |
| SCHEMBL7609416 | 0.67 | SLC6A2 (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL10384652 | 0.66 | MAPT (0.62) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL8426026 | 0.66 | SLC6A2 (0.38) | MEN1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019434-B1 | INHIBITORS OF METALLOPROTEINASES, THEIR THERAPEUTIC USE, AND PROCESS FOR THE PRODUCTION OF THE STARTING COMPOUND IN THEIR SYNTHESIS | POLIFARMA SPA (IT) | 2003-10-01 | — | — | EP | disclosed |