Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004125 | 0.83 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL2004120 | 0.83 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL852209 | 0.82 | SLC1A3 (0.76) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL418322 | 0.82 | SLC1A3 (0.76) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL1953602 | 0.82 | SLC1A3 (0.76) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL8840019 | 0.81 | SLC1A2 (0.65) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| Water SCHEMBL30419716 | 0.81 | SLC1A3 (0.73) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL2000767 | 0.80 | SLC1A2 (0.63) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL2000459 | 0.79 | SLC1A2 (0.61) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 | |
| SCHEMBL23867724 | 0.78 | ALDH1A1 (0.45) | SLC1A2SLC1A1SLC1A3MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528503-B2 | Anticoagulants | MERCK & CO., INC. | 2003-03-04 | — | — | US | disclosed |
| US-20030013700-A1 | Thrombin inhibitors | MERCK SHARP & DOHME CORP. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013700-A1 | Thrombin inhibitors | TFPI, PLAT, TFPI2 | SLC1A2 3541/4885SLC1A1 2916/4885SLC1A3 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.