SCHEMBL7108778

SCHEMBL7108778

CC1=C([Si](C)(C)C2=C(C)[CH]c3c(C)ccc(C)c32)c2c(C)ccc(C)c2[CH]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.31
POR P16435 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7111668 0.67
SCHEMBL4160455 0.59 ALDH1A1 (0.44) NQO1POR
SCHEMBL15349384 0.59 NOS3 (0.30)
SCHEMBL3998653 0.58
SCHEMBL1028158 0.56 ALDH1A1 (0.36)
SCHEMBL30492233 0.56 CDC25B (0.39) NQO1POR
SCHEMBL27374485 0.56 CDC25B (0.39) NQO1POR
SCHEMBL6152288 0.56 NQO1 (0.52) NQO1POR
SCHEMBL1886099 0.56 NQO1 (0.41) NQO1POR
SCHEMBL19729087 0.55 ALDH1A1 (0.42) NQO1POR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed