Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239226 | 0.77 | HEXA (0.34) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL6234169 | 0.77 | PDCD1 (0.38) | — | |
| SCHEMBL6344310 | 0.76 | FGFR1 (0.36) | FGFR1FGFR2FGFR4FGFR3CDC25A | |
| SCHEMBL4621848 | 0.75 | CDC25A (0.38) | CDC25ACDC25BMAP2K7S100A4AURKA | |
| SCHEMBL9068235 | 0.65 | TSHR (0.47) | CDC25ACDC25BMAP2K7S100A4AURKA | |
| SCHEMBL7270538 | 0.64 | CDC25A (0.32) | CDC25ACDC25BMAP2K7S100A4AURKA | |
| SCHEMBL6344388 | 0.64 | CDC25A (0.36) | CDC25ACDC25BMAP2K7S100A4AURKA | |
| SCHEMBL571496 | 0.64 | MAPT (0.56) | FGFR1FGFR2FGFR4FGFR3CDC25A | |
| SCHEMBL7030691 | 0.63 | GABRA1 (0.38) | CDC25ACDC25BMAP2K7S100A4 | |
| SCHEMBL7107949 | 0.63 | MAPT (0.37) | FGFR1FGFR2FGFR4FGFR3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |
| US-6143686-A | FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER | EXXON CHEMICAL PATENTS, INC. (US) | 2000-11-07 | — | — | US | claimed |
| US-6143686-A | FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER | EXXON CHEMICAL PATENTS, INC. (US) | 2000-11-07 | — | — | US | disclosed |