SCHEMBL6239226

SCHEMBL6239226

CCC1=C(C)c2c(C)cccc2[C]1[SiH2][C]1C(CC)=C(C)c2c(C)cccc21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
MYC P01106 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
HTR7 P34969 1/20 0.32
FGFR1 P11362 1/20 0.30
FGFR2 P21802 1/20 0.30
FGFR4 P22455 1/20 0.30
FGFR3 P22607 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234169 0.81 PDCD1 (0.38) HEXAHEXBHTR7
SCHEMBL7108786 0.77 FGFR1 (0.33) FGFR1FGFR2FGFR4FGFR3
SCHEMBL7030691 0.69 GABRA1 (0.38)
SCHEMBL28657256 0.66 MYC (0.33) MYCCA1CA2CA7CA9
SCHEMBL4161420 0.63 CA1 (0.48) MYCCA1CA2CA7CA9
SCHEMBL2044927 0.63 CA1 (0.41) MYCCA1CA2CA7CA9
SCHEMBL1132663 0.63 MYC (0.50) HEXAHEXBMYCCA1CA2
SCHEMBL9629385 0.62 FGFR1 (0.38) MYCCA1CA2CA7CA9
SCHEMBL28899579 0.61 MYC (0.58) MYCCA1CA2CA7CA9
SCHEMBL28335244 0.60 CYP3A4 (0.37) MYCCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO disclosed
EP-1311593-A2 POLYPROPYLENE FILMS Exxonmobil Chemical Patents Inc. (US) 2003-05-21 EP disclosed
US-20020052446-A1 Composition based on monofluorometal complexes BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 US disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed