Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110470 | 0.84 | MEN1 (0.43) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7105591 | 0.84 | MEN1 (0.43) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7110901 | 0.84 | MEN1 (0.43) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7109650 | 0.83 | MEN1 (0.41) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7774527 | 0.79 | MEN1 (0.43) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7105628 | 0.78 | MEN1 (0.45) | MEN1KMT2AHSD17B10CACNA1BPSMB8 | |
| SCHEMBL5347579 | 0.77 | CACNA1B (0.52) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7110494 | 0.77 | CACNA1B (0.50) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7109484 | 0.75 | USP21 (0.40) | MEN1KMT2AHSD17B10ATMCACNA1B | |
| SCHEMBL7768814 | 0.75 | CACNA1B (0.39) | MEN1KMT2ACACNA1BPSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | MEN1 2633/4885KMT2A 1929/4885HSD17B10 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.