Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105591 | 1.00 | MEN1 (0.43) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7110901 | 1.00 | MEN1 (0.43) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7105628 | 0.93 | MEN1 (0.45) | MEN1KMT2ACACNA1BHSD17B10PSMB8 | |
| SCHEMBL7110494 | 0.92 | CACNA1B (0.50) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7768814 | 0.91 | CACNA1B (0.39) | MEN1KMT2ACACNA1BPSMB8PSMB5 | |
| SCHEMBL7105221 | 0.90 | ATM (0.39) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7111673 | 0.90 | YAP1 (0.46) | CACNA1BATMHSD17B10PSMB8PSMB5 | |
| SCHEMBL7109484 | 0.89 | USP21 (0.40) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7105548 | 0.88 | HSD17B10 (0.39) | MEN1KMT2ACACNA1BATMHSD17B10 | |
| SCHEMBL7774825 | 0.88 | CACNA1B (0.44) | CACNA1BPSMB8PSMB5ALDH1A1BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | MEN1 2633/4885KMT2A 1929/4885CACNA1B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.