Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372064 | 0.77 | HPGD (0.44) | HSPA5NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2428932 | 0.76 | NPC1 (0.45) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL20292624 | 0.74 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL6663162 | 0.73 | NPC1 (0.42) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL3810267 | 0.73 | PRMT5 (0.41) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL17512674 | 0.72 | CTSK (0.43) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL11252147 | 0.72 | PRMT5 (0.47) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL26528219 | 0.72 | SMN1; SMN2 (0.45) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL12533604 | 0.71 | PRMT5 (0.50) | HSPA5NPC1RAB9APRMT5WDR77 | |
| SCHEMBL8872434 | 0.71 | EGLN1 (0.47) | HSPA5NPC1RAB9APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |