Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847414 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AHCRTR2GRM5SMN1; SMN2 | |
| SCHEMBL2847417 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AHCRTR2GRM5SMN1; SMN2 | |
| SCHEMBL2853507 | 0.77 | ELOVL6 (0.47) | ALDH1A1KMT2AGRM5RAB9ASMN1; SMN2 | |
| SCHEMBL2853508 | 0.77 | ELOVL6 (0.47) | ALDH1A1KMT2AGRM5RAB9ASMN1; SMN2 | |
| SCHEMBL15271041 | 0.76 | EHMT2 (0.50) | ALDH1A1KMT2AHCRTR2GRM5RAB9A | |
| SCHEMBL15271518 | 0.73 | EHMT2 (0.50) | ALDH1A1KMT2AHCRTR2GRM5RAB9A | |
| SCHEMBL30714506 | 0.72 | GRM5 (0.76) | KMT2AGRM5PKMSMN1; SMN2 | |
| SCHEMBL26923195 | 0.72 | GRM5 (0.76) | KMT2AGRM5PKMSMN1; SMN2 | |
| SCHEMBL710521 | 0.72 | ELOVL6 (0.42) | ALDH1A1GRM5HSD11B1PKMRAB9A | |
| SCHEMBL12949631 | 0.71 | EHMT2 (0.48) | ALDH1A1KMT2AHCRTR2GRM5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124807-B2 | Sulfonyl-substituted 6-membered ring derivative | MSD K.K. (JP) | 2012-02-28 | — | — | US | disclosed |