Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106920 | 0.96 | HSD11B1 (0.38) | HSD11B1TLR8RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7110767 | 0.95 | KDM4E (0.38) | HSD11B1TLR8RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7103912 | 0.95 | HSD11B1 (0.37) | HSD11B1TLR8RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7108900 | 0.93 | KDM4E (0.40) | HSD11B1TLR8RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7111531 | 0.93 | KDM4E (0.40) | HSD11B1TLR8RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7105395 | 0.93 | TLR8 (0.34) | HSD11B1TLR8RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7109432 | 0.91 | KDM4E (0.41) | HSD11B1TLR8RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7108745 | 0.90 | KDM4E (0.40) | HSD11B1TLR8RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7109744 | 0.90 | SMN1; SMN2 (0.34) | HSD11B1TLR8RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7111520 | 0.88 | TLR8 (0.38) | HSD11B1TLR8RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |