Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109460 | 0.95 | GCGR (0.38) | SMN1; SMN2NPC1TSHRRAB9AGCGR | |
| SCHEMBL7108902 | 0.92 | CRHR1 (0.34) | SMN1; SMN2NPC1TSHRRAB9AGCGR | |
| SCHEMBL7106920 | 0.91 | HSD11B1 (0.38) | SMN1; SMN2NPC1TSHRRAB9ATLR8 | |
| SCHEMBL7109565 | 0.90 | HSD11B1 (0.35) | SMN1; SMN2NPC1TSHRRAB9ATLR8 | |
| SCHEMBL7105395 | 0.90 | TLR8 (0.34) | SMN1; SMN2NPC1TSHRRAB9ATLR8 | |
| SCHEMBL7108900 | 0.88 | KDM4E (0.40) | SMN1; SMN2TSHRRAB9AADORA3TLR8 | |
| SCHEMBL7105422 | 0.88 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9AADORA3LMNA | |
| SCHEMBL7110309 | 0.88 | UCHL3 (0.37) | GCGR | |
| SCHEMBL7111531 | 0.88 | KDM4E (0.40) | SMN1; SMN2TSHRRAB9AADORA3TLR8 | |
| SCHEMBL7103912 | 0.87 | HSD11B1 (0.37) | SMN1; SMN2NPC1TSHRRAB9ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |