Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253865 | 0.73 | KDM4E (0.46) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL136053 | 0.67 | NOX1 (0.38) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL4369752 | 0.67 | — | — | |
| SCHEMBL1996673 | 0.64 | MAPT (0.38) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL4824 | 0.64 | — | — | |
| SCHEMBL20554671 | 0.64 | MAPT (0.38) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL29848588 | 0.64 | MAPT (0.38) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL4125447 | 0.60 | PLAU (0.39) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL5612975 | 0.59 | GAA (0.41) | PLAUCA12CA1CA2CA9 | |
| SCHEMBL5613285 | 0.59 | ALDH1A1 (0.32) | GRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166651-A1 | Novel 3-substituted 1,2,4-benzotriazines, a method for their production and the use thereof | UFZ UMWELTFORSCHUNGSZENTRUM LEIPZIG-HALLE GMBH (DE) | 2003-09-04 | — | — | US | claimed |
| US-20030166651-A1 | Novel 3-substituted 1,2,4-benzotriazines, a method for their production and the use thereof | UFZ UMWELTFORSCHUNGSZENTRUM LEIPZIG-HALLE GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166651-A1 | Novel 3-substituted 1,2,4-benzotriazines, a method for their production and the use thereof | RYR2, CACNA1I, BRCA1 | PLAU 4594/4885CA12 2158/4885CA1 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.