Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848588 | 1.00 | MAPT (0.38) | MAPTGAANOX1MEN1KMT2A | |
| SCHEMBL4824 | 0.77 | — | — | |
| SCHEMBL20554671 | 0.77 | MAPT (0.38) | MAPTGAANOX1MEN1KMT2A | |
| SCHEMBL168935 | 0.73 | PDGFRA (0.52) | GAAMEN1KMT2AMAOAPOLB | |
| SCHEMBL6785405 | 0.73 | NOS2 (0.32) | BCHEACHEALOX15PLAUHSD17B10 | |
| SCHEMBL17080876 | 0.71 | PARP1 (0.47) | MAPTGAAMEN1KMT2AALOX15 | |
| SCHEMBL2427433 | 0.71 | ACVR1 (0.40) | MAPTGAANOX1MEN1KMT2A | |
| SCHEMBL3402020 | 0.68 | GAA (0.39) | MAPTGAA | |
| SCHEMBL624418 | 0.67 | GAA (0.59) | MAPTGAANOX1MEN1KMT2A | |
| SCHEMBL29369547 | 0.67 | GAA (0.59) | MAPTGAANOX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930620-A | Tetrafused ring compound, preparation method, pharmaceutical composition and application thereof | 和径医药科技（上海）有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119591594-A | Preparation method of tetrahydropyridine molecules with photooxidation luminescence effect | 南开大学 | 2025-03-11 | — | — | CN | disclosed |
| US-20240376084-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2024-11-14 | — | — | US | disclosed |
| US-12037405-B2 | Anti-CD70 antibody drug conjugates | AMBRX, INC. | 2024-07-16 | — | — | US | disclosed |
| EP-3604288-B1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | DEV CT BIOTECHNOLOGY (TW) | 2024-04-10 | — | — | EP | disclosed |
| EP-3488870-B1 | ANTI-CD70 ANTIBODY DRUG CONJUGATES | AMBRX INC (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-116891540-A | Alginic acid derivatives with non-steroidal anti-inflammatory compounds attached thereto | 持田制药株式会社 | 2023-10-17 | — | — | CN | disclosed |
| US-20230322756-A1 | FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230295320-A1 | Anti-CD70 Antibody Drug Conjugates | AMBRX, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230250077-A1 | SULFONYLBENZAMIDE DERIVATIVE AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| WO-1995012417-A1 | ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS | ACEA PHARMACEUTICALS, INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994000124-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | WEBER ECKARD (US) | 1994-01-06 | — | — | WO | disclosed |
| US-5175221-A | Oxidation and heat resistant; stability | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5149773-A | Using a transition metal sulfide catalyst | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| US-5114610-A | Lewis acids dissolved in aprotic organic solvents | HONEYWELL INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0444807-A1 | Polyquinoxaline compositions and their method of preparation | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4963616-A | N-HETERO MACROMOLECULAR, RIGID CHAIN OR LADDER POLYMERS COM-PLEXED WITH LEWIS ACIDS | HONEYWELL INC. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4945156-A | DECOMPLEXING POLYMER-LEWIS ACID COMPLEX TO REGENERATE | HONEYWELL INC. (US) | 1990-07-31 | — | — | US | disclosed |
| US-4582923-A | REACTING PRIMARY AMINE, CARBON MONOXIDE AND HYDROXYL COMPOUND IN PRESENCE OF PALLADIUM OR PALLADIUM COMPOUND AND OXIDIZING QUINOID, REDOX CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037405-B2 | Anti-CD70 antibody drug conjugates | CD74, CD63, CD47 | MAPT 3639/4885GAA 438/4885NOX1 4543/4885 |
| US-20230322756-A1 | FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | GLP1R, GIPR, VIP | MAPT 4126/4885GAA 1954/4885NOX1 2221/4885 |
| US-20240376084-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | SERPINB1, LTA, SERPINC1 | MAPT 4709/4885GAA 1160/4885NOX1 1970/4885 |
| US-20230295320-A1 | Anti-CD70 Antibody Drug Conjugates | CD63, CD74, CD99 | MAPT 3693/4885GAA 529/4885NOX1 4634/4885 |
| US-20230250077-A1 | SULFONYLBENZAMIDE DERIVATIVE AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | GLP1R, HADHB, SUCNR1 | MAPT 4649/4885GAA 1097/4885NOX1 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.