SCHEMBL7109719

SCHEMBL7109719

CC(CO)(c1ccccc1)c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
CYP3A4 P08684 2/20 0.39
KIF11 P52732 1/20 0.39
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
KCNA5 P22460 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK1 P28482 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956673 0.88 CYP2C19 (0.42) ALDH1A1TSHRTDP1ESR1ESR2
SCHEMBL1836839 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTDP1ESR1ESR2
SCHEMBL6432386 0.82 ESR1 (0.45) ALDH1A1TSHRTDP1ESR1ESR2
SCHEMBL1844955 0.81 ALDH1A1 (0.48) ALDH1A1TSHRTDP1ESR1ESR2
SCHEMBL7292617 0.81 CYP2C19 (0.46) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL9233872 0.79 ESR1 (0.48) ALDH1A1ESR1ESR2CYP3A4CYP2C19
SCHEMBL3963329 0.78 ALDH1A1 (0.48) ALDH1A1TSHRTDP1ESR1ESR2
SCHEMBL3967693 0.77 ALDH1A1 (0.62) ALDH1A1TSHRTDP1CYP3A4KIF11
SCHEMBL27706717 0.76 CNR1 (0.43) ALDH1A1TSHRTDP1CNR1CNR2
SCHEMBL15459418 0.76 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CYP3A4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348005-A1 FLAME RETARDANT CARBONATE POLYMERS AND USE THEREOF 3M Innovative Properties Company (US) 2003-10-01 EP disclosed
WO-2002051925-A1 FLAME RETARDANT CARBONATE POLYMERS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-07-04 WO disclosed