SCHEMBL6432386

SCHEMBL6432386

CC(CO)(c1ccccc1)c1ccc(O)c(C(C)(CO)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.45
ESR2 Q92731 3/20 0.45
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 1/20 0.39
KLF10 Q13118 1/20 0.39
CHEK1 O14757 1/20 0.38
FYN P06241 1/20 0.38
PDGFRB P09619 1/20 0.38
PIM1 P11309 1/20 0.38
FGFR1 P11362 1/20 0.38
FLT1 P17948 1/20 0.38
GRK5 P34947 1/20 0.38
MAP2K2 P36507 1/20 0.38
MAPK8 P45983 1/20 0.38
CDK8 P49336 1/20 0.38
RPS6KA3 P51812 1/20 0.38
PRKX P51817 1/20 0.38
JAK3 P52333 1/20 0.38
LIMK1 P53667 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15846818 0.83 ESR1 (0.45) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL7109719 0.82 ALDH1A1 (0.52) ESR1ESR2ALDH1A1CYP3A4TDP1
SCHEMBL9233872 0.82 ESR1 (0.48) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL30471649 0.81 ESR1 (0.42) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL9233917 0.80 ESR1 (0.41) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL7292617 0.80 CYP2C19 (0.46) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL2014300 0.78 ESR2 (0.63) ESR1ESR2ALDH1A1CYP3A4TDP1
SCHEMBL8956673 0.78 CYP2C19 (0.42) ESR1ESR2ALDH1A1CYP3A4CYP2D6
SCHEMBL7510606 0.74 ESR1 (0.63) ESR1ESR2ALDH1A1KLF10TDP1
SCHEMBL7943504 0.72 ALOX15 (0.58) ESR1ESR2ALDH1A1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348005-B1 FLAME RETARDANT CARBONATE POLYMERS AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2005-03-16 EP disclosed
US-6518347-B1 For producing shaped articles 3M INNOVATIVE PROPERTIES COMPANY 2003-02-11 US disclosed
US-20030022971-A1 FLAME RETARDANT CARBONATE POLYMERS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2003-01-30 US disclosed
EP-0581074-B1 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI CHEMICALS INC (JP) 1999-03-10 EP disclosed
EP-0346761-B1 Process for the preparation of aromatic polycarbonates BAYER AG (DE) 1994-12-21 EP disclosed
US-5360658-A Packaging electronic components BAYER AKTIENGESELLSCHAFT (DE) 1994-11-01 US disclosed
US-5359117-A Continuous processing using molecular weight control agent, catalyst, carbonyl halide, solvent and base MITSUI TOATSU CHEMICALS, INC. (JP) 1994-10-25 US disclosed
EP-0581074-A2 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-02-02 EP disclosed
EP-0561240-A2 Antistatic polycarbonate extruded films BAYER AG (DE) 1993-09-22 EP disclosed
EP-0249101-B1 MOULDED ARTICLES CONTAINING CARBON BAYER AG (DE) 1992-01-02 EP disclosed
EP-0346761-A2 Process for the preparation of aromatic polycarbonates BAYER AG (DE) 1989-12-20 EP disclosed
US-4876033-A MOLDING BLENDS OF POLYCARBONATES, POLYBUTYLENE TEREPHTHALATE AND CARBON BLACK; PACKAGING FOR ELECTRONIC EQUIPMENT BAYER AKTIENGESELLSCHAFT (DE) 1989-10-24 US disclosed
EP-0337207-A2 Preparation process of aromatic polycarbonates, aromatic polyestercarbonates and aromatic polyesters BAYER AG (DE) 1989-10-18 EP disclosed
EP-0120394-B1 FIRE-RESISTANT POLYCARBONATE HOLLOW PANELS BAYER AG (DE) 1989-01-18 EP disclosed
US-4774273-A ELECTRICAL SUPPLIES, HOUSINGS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-27 US disclosed
EP-0249101-A2 Moulded articles containing carbon BAYER AG (DE) 1987-12-16 EP disclosed
EP-0170851-B1 ARYL ESTER OF PERFLUOROALKANE-SULPHONIC ACID AS AN ANTIDRIPPING AGENT IN FLAME-RESISTANT COMPOSITIONS BASED ON THERMOPLASTIC AROMATIC POLYCARBONATES BAYER AG (DE) 1987-09-09 EP disclosed
EP-0170851-A1 Aryl ester of perfluoroalkane-sulphonic acid as an antidripping agent in flame-resistant compositions based on thermoplastic aromatic polycarbonates BAYER AG (DE) 1986-02-12 EP disclosed
EP-0120394-A1 Fire-resistant polycarbonate hollow panels BAYER AG (DE) 1984-10-03 EP disclosed
EP-0013904-B1 PROCESS FOR THE PREPARATION OF POLYCARBONATES BAYER AG (DE) 1983-03-09 EP disclosed