Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2973570 | 0.76 | ALDH1A1 (0.49) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL12858739 | 0.71 | ALDH1A1 (1.00) | ALDH1A1NPSR1MAPT | |
| SCHEMBL4485788 | 0.70 | PAK1 (0.47) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL11138518 | 0.70 | ALDH1A1 (0.52) | ALDH1A1NPSR1HTTKDM4ELMNA | |
| SCHEMBL7595557 | 0.70 | ALDH1A1 (0.43) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL6552668 | 0.70 | ABHD16A (0.46) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL27468639 | 0.69 | ALDH1A1 (0.56) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL6551189 | 0.68 | ALDH1A1 (0.41) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL5271670 | 0.68 | ALDH1A1 (0.48) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL5271667 | 0.68 | ALDH1A1 (0.48) | ALDH1A1NPSR1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152024-C | Substituted 3-phenyl-5-alkoxy-1, 3, 4-oxadiazol-2-ones and their use as lipase inhibitors | ���ĵ�˹ҩ��¹�����˾ | 2004-06-02 | — | — | CN | disclosed |
| EP-1214302-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6596742-B1 | Inhibitory effect on the hormone-sensitive lipase, HSL. insecticides, controlling metabolism and multistage synthesis | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-22 | — | — | US | disclosed |
| EP-1214302-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001017981-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-03-15 | — | — | WO | disclosed |