Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858739 | 0.72 | ALDH1A1 (1.00) | ALDH1A1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL7109847 | 0.69 | ALDH1A1 (0.55) | ALDH1A1NPSR1HTTMAPTLMNA | |
| SCHEMBL11138518 | 0.68 | ALDH1A1 (0.52) | ALDH1A1NPSR1HTTTDP1LMNA | |
| SCHEMBL10072925 | 0.68 | ALDH1A1 (0.50) | ALDH1A1NPSR1HTTTDP1LMNA | |
| SCHEMBL13469360 | 0.68 | L3MBTL1 (0.53) | ALDH1A1NPSR1HTTL3MBTL1MAPT | |
| SCHEMBL2973570 | 0.67 | ALDH1A1 (0.49) | ALDH1A1NPSR1HTTL3MBTL1MAPT | |
| SCHEMBL28209554 | 0.66 | ALDH1A1 (0.45) | ALDH1A1NPSR1HTTTDP1LMNA | |
| SCHEMBL28209533 | 0.65 | ALDH1A1 (0.47) | ALDH1A1NPSR1HTTL3MBTL1MAPT | |
| SCHEMBL17010541 | 0.65 | ALDH1A1 (0.47) | ALDH1A1NPSR1HTTL3MBTL1MAPT | |
| SCHEMBL5271670 | 0.64 | ALDH1A1 (0.48) | ALDH1A1NPSR1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152024-C | Substituted 3-phenyl-5-alkoxy-1, 3, 4-oxadiazol-2-ones and their use as lipase inhibitors | ���ĵ�˹ҩ��¹�����˾ | 2004-06-02 | — | — | CN | disclosed |