⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84084 | 1.00 | — | — | |
| SCHEMBL8758532 | 0.98 | FAAH (0.57) | — | |
| SCHEMBL21423341 | 0.98 | FAAH (0.57) | — | |
| SCHEMBL3391061 | 0.98 | FAAH (0.57) | — | |
| Hydrogen Sulfide SCHEMBL23406532 | 0.98 | TRPA1 (0.52) | — | |
| Hydrogen Sulfide SCHEMBL23406476 | 0.98 | TRPA1 (0.52) | — | |
| SCHEMBL812162 | 0.98 | FAAH (0.57) | — | |
| SCHEMBL872361 | 0.98 | FAAH (0.57) | — | |
| SCHEMBL12198766 | 0.98 | FAAH (0.57) | — | |
| SCHEMBL2301761 | 0.98 | FAAH (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1437580-A | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-08-20 | — | — | CN | claimed |
| US-20030072725-A1 | Topical cosmetic agents containing 2-hydrazino-1,3 -heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-04-17 | — | — | US | claimed |
| CN-1406122-A | Topical cosmetic agents containing 2-hydrazino-1,3-heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-03-26 | — | — | CN | claimed |
| US-20020128268-A1 | Use of 2-hydrazino-1,3-thiazoles as antioxidants | HAARMANN & REIMER GMBH (DE) | 2002-09-12 | — | — | US | claimed |
| CN-1437580-A | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-08-20 | — | — | CN | disclosed |
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-07-24 | — | — | US | disclosed |
| US-20030072725-A1 | Topical cosmetic agents containing 2-hydrazino-1,3 -heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-04-17 | — | — | US | disclosed |
| CN-1406122-A | Topical cosmetic agents containing 2-hydrazino-1,3-heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-03-26 | — | — | CN | disclosed |
| US-20020128268-A1 | Use of 2-hydrazino-1,3-thiazoles as antioxidants | HAARMANN & REIMER GMBH (DE) | 2002-09-12 | — | — | US | disclosed |