Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890691 | 0.97 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL4623138 | 0.95 | PDCD1 (0.39) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL3998331 | 0.94 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL27489709 | 0.93 | SOAT1 (0.37) | ACHE | |
| SCHEMBL28807858 | 0.92 | BCHE (0.36) | PDCD1CD274KDM4ELMNATP53 | |
| SCHEMBL27546243 | 0.89 | PDCD1 (0.35) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL5084813 | 0.89 | PDCD1 (0.39) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL1453704 | 0.88 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL1452035 | 0.87 | ALDH1A1 (0.40) | PDCD1CD274 | |
| SCHEMBL8679512 | 0.86 | PDCD1 (0.37) | PDCD1CD274CHRNB2CHRNA4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |