Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454411 | 0.93 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4HTR2A | |
| SCHEMBL1453005 | 0.91 | ALDH1A1 (0.40) | PDCD1CD274ALDH1A1MAPK1 | |
| SCHEMBL4623138 | 0.90 | PDCD1 (0.39) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL6890691 | 0.89 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL7110286 | 0.89 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL3998331 | 0.89 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL27478943 | 0.87 | PDCD1 (0.40) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL8679512 | 0.87 | PDCD1 (0.37) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL1241178 | 0.86 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4HTR7 | |
| SCHEMBL1453454 | 0.85 | PGR (0.36) | PDCD1CD274HTR2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832866-B1 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | BASELL POLYOLEFINE GMBH (DE) | 2002-01-09 | — | — | EP | claimed |
| EP-0946610-B1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0751143-B1 | Process for the preparation of carbon bridged dicyclopentadiene compounds | BASELL POLYOLEFINE GMBH (DE) | 2001-09-05 | — | — | EP | claimed |
| EP-0832866-A2 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | TARGOR GmbH (DE) | 1998-04-01 | — | — | EP | claimed |
| EP-0751143-A2 | Process for the preparation of carbon bridged dicyclopentadiene compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-02 | — | — | EP | claimed |
| EP-1954724-A1 | SYNDIOTACTIC PROPYLENE ELASTOMERS | ExxonMobil Chemical Patents Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007061525-A1 | SYNDIOTACTIC PROPYLENE ELASTOMERS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-0832866-B1 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | BASELL POLYOLEFINE GMBH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0751143-B1 | Process for the preparation of carbon bridged dicyclopentadiene compounds | BASELL POLYOLEFINE GMBH (DE) | 2001-09-05 | — | — | EP | disclosed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| JP-2001011089-A | TRANSITION METAL COMPOUND, CATALYST COMPOSITION, ITS PREPARATIVE METHOD AND ITS USE FOR OLEFIN POLYMERIZATION | TARGOR GMBH | 2001-01-16 | — | — | JP | disclosed |
| EP-1052263-A2 | Transition-metal compounds, catalyst systems, process for their preparation and use in the polymerisation of olefins | TARGOR GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0924322-A1 | Conjugate fibers and non-woven fabrics therefrom | Mitsui Chemicals, Inc. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0832866-A2 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | TARGOR GmbH (DE) | 1998-04-01 | — | — | EP | disclosed |
| EP-0751143-A2 | Process for the preparation of carbon bridged dicyclopentadiene compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-02 | — | — | EP | disclosed |