Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 2/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 4/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111074 | 0.93 | PNP (0.44) | SMN1; SMN2KMT2APNPADORA2APDE10A | |
| SCHEMBL7111857 | 0.93 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTUBE2NKMT2A | |
| SCHEMBL7120152 | 0.92 | PNP (0.45) | SMN1; SMN2KMT2APNPMAPK1ADORA2A | |
| SCHEMBL7117280 | 0.89 | PNP (0.45) | SMN1; SMN2LMNAHTTKMT2APNP | |
| SCHEMBL7111860 | 0.89 | PNP (0.45) | SMN1; SMN2LMNAHTTKMT2APNP | |
| SCHEMBL7118541 | 0.86 | PNP (0.40) | SMN1; SMN2KMT2APNPADORA2A | |
| SCHEMBL7113849 | 0.86 | PNP (0.43) | SMN1; SMN2KMT2APNPMAPK1ADORA2A | |
| SCHEMBL7113168 | 0.86 | PNP (0.43) | SMN1; SMN2KMT2APNPMAPK1ADORA2A | |
| SCHEMBL7113866 | 0.86 | PNP (0.39) | SMN1; SMN2PNPADORA2APDE10A | |
| SCHEMBL7113247 | 0.86 | PNP (0.39) | SMN1; SMN2KMT2APNPMAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | claimed |
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | TERT, TERF2IP, TERF2 | SMN1; SMN2 2003/4885LMNA 1848/4885HTT 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.