SCHEMBL7110378

SCHEMBL7110378

CCC(F)C(=O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
FFAR3 O14843 2/20 0.36
MAPT P10636 1/20 0.35
CES2 O00748 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
CPA1 P15085 1/20 0.31
ACE2 Q9BYF1 1/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1304206 0.77 USP2 (0.42) LDHASRRFFAR3HDAC3HDAC1
SCHEMBL27790068 0.77 LDHA (0.40) LDHASRR
SCHEMBL7099707 0.76 MGAM (0.42) CES2TSHR
SCHEMBL10285369 0.76
SCHEMBL10867392 0.74
SCHEMBL2021291 0.74 USP2 (0.44) LDHASRRFFAR3HDAC3HDAC1
SCHEMBL7096992 0.73 GAA (0.56) TSHR
SCHEMBL134555 0.73
SCHEMBL30730720 0.73
SCHEMBL323205 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406361-A Practical production method for 3, 3-difluoro-2-hydroxypropionic acid 中央硝子株式会社 2017-11-28 CN disclosed
EP-1174415-B1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PROD & CHEM (US) 2003-10-22 EP disclosed
EP-1174415-A1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-01-23 EP disclosed
US-6307105-B1 ELECTROPHILICALLY FLUORINATING A BETA-DICARBONYL WITH BIS(FLUOROXY)DIFLUOROMETHANE IN THE PRESENCE OF AN ACID AIR PRODUCTS AND CHEMICALS, INC. 2001-10-23 US disclosed