Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655574 | 0.92 | THRB (0.43) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL59221 | 0.90 | THRB (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL218038 | 0.89 | ALDH1A1 (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL23045188 | 0.89 | ALDH1A1 (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL194259 | 0.87 | ALDH1A1 (0.46) | THRBTSHRALDH1A1TP53CYP3A4 | |
| Ether SCHEMBL2459087 | 0.86 | THRB (0.50) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL215988 | 0.85 | ALDH1A1 (0.44) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL1030890 | 0.85 | TSHR (0.47) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL33308 | 0.85 | TSHR (0.47) | THRBTSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL15234 | 0.85 | TSHR (0.47) | THRBTSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474383-B | Free radical polymerizable composition | 波林复合材料美国股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2019142955-A1 | COLORED PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER COMPRISING BLACK MATRIX, COLUMN SPACER OR BLACK COLUMN SPACER MANUFACTURED BY USING SAME, AND DISPLAY DEVICE COMPRISING SAME COLOR FILTER | 동우 화인켐 주식회사 | 2019-07-25 | — | — | WO | disclosed |
| US-9597858-B2 | Method for manufacturing touch panel and molded article | PANAC CO., LTD. (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160009056-A1 | METHOD FOR MANUFACTURING TOUCH PANEL, TOUCH PANEL, METHOD FOR MANUFACTURING MOLDED ARTICLE, MOLDED ARTICLE, AND LAMINATED FILM | PANAC CO., LTD. (JP) | 2016-01-14 | — | — | US | disclosed |
| CN-102341731-A | Coloring composition, color filter and color liquid crystal display element | JSR CORP | 2012-02-01 | — | — | CN | disclosed |
| US-20030232193-A1 | Dry film resist and printed circuit board producing method | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-18 | — | — | US | disclosed |