Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110628 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL4463525 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL10866750 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL10867362 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL9687983 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL10865027 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL10866178 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL9514136 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL9070383 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 | |
| SCHEMBL9687866 | 0.98 | USP2 (0.48) | ALDH1A1CNR1CNR2USP2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280753-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | Rhodia/Chirex, Inc. (US) | 2003-02-05 | — | — | EP | claimed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | claimed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | claimed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | claimed |
| EP-1280753-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | Rhodia/Chirex, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | TOP1, POLN, RIF1 | ALDH1A1 180/4885CNR1 3118/4885CNR2 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.