SCHEMBL7110628

SCHEMBL7110628

CCCCCOC(C)CO

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
USP2 O75604 1/20 0.45
DNM1 Q05193 1/20 0.43
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.39
LPAR1 Q92633 6/20 0.38
LPAR3 Q9UBY5 6/20 0.38
LPAR2 Q9HBW0 3/20 0.38
LPAR6 P43657 2/20 0.38
LPAR4 Q99677 2/20 0.38
LPAR5 Q9H1C0 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110620 1.00 ALDH1A1 (0.47) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL4463525 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL10866750 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL10867362 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL9687983 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL10865027 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL10866178 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL9514136 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL9070383 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1
SCHEMBL9687866 0.98 USP2 (0.48) ALDH1A1CNR1CNR2USP2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280753-A1 PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL Rhodia/Chirex, Inc. (US) 2003-02-05 EP claimed
US-6448449-B2 RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; RHODIA CHIREX, INC. 2002-09-10 US claimed
US-20020007090-A1 Process for preparation of (R)-1- (aryloxy)propan-2-ol RHODIA CHIREX, INC. 2002-01-17 US claimed
WO-2001081286-A1 PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL RHODIA/CHIREX, INC. (US) 2001-11-01 WO claimed
EP-0175591-A2 Lactic acid derivative, liquid crystal composition containing same and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1986-03-26 EP claimed
US-4065576-A OLEIC ACID AND SALTS WEYERHAEUSER COMPANY (US) 1977-12-27 US claimed
EP-4213627-A1 STABILIZATION OF THIOKETONES ON SURFACES Bayer Aktiengesellschaft (DE) 2023-07-26 EP disclosed
US-20220183279-A1 STABILIZED THIOKETONE FORMULATIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-06-16 US disclosed
CN-111093374-B STABILIZED PROSTABILIZER-CONTAINING FORMULATIONS WITH LOW 2- (1-CHLOROCYCLOPROPYL) -1- (2-CHLOROPHENYL) -3- (1H-1,2, 4-TRIAZOL-1-YL) PROPAN-2-OL CONTENT 拜耳股份公司 2022-06-10 CN disclosed
WO-2022058522-A1 STABILIZATION OF THIOKETONES ON SURFACES BAYER AKTIENGESELLSCHAFT (DE) 2022-03-24 WO disclosed
EP-3941199-A1 STABILIZED THIOKETONE FORMULATIONS Bayer Aktiengesellschaft (DE) 2022-01-26 EP disclosed
CN-113710091-A Stable formulations of thiones 拜耳公司 2021-11-26 CN disclosed
WO-2020187871-A1 STABILIZED THIOKETONE FORMULATIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-09-24 WO disclosed
US-4880560-A ENANTIOMORPHS, PHENYL OR BIPHENYL CARBOXYLIC ACID CANON KABUSHIKI KAISHA (JP) 1989-11-14 US disclosed
US-4818429-A FERROELECTRIC LIQUID CRYSTAL DISPLAY ELEMENTS; GOOD RESPONSE CHISSO CORPORATION (JP) 1989-04-04 US disclosed
US-4812259-A POLARIZATION, FERROELECTRICITY CANON KABUSHIKI KAISHA (JP) 1989-03-14 US disclosed
EP-0260153-A2 Cyclohexylphenylpyridazines Chisso Corporation (JP) 1988-03-16 EP disclosed
EP-0255962-A2 Optically active mesomorphic compound CANON KABUSHIKI KAISHA (JP) 1988-02-17 EP disclosed
EP-0170121-A1 2-Hydroxy-3-aryloxypropyl or 2-hydroxy-2-benzofuranyl ethyl tertiary amine having an anti-hyperglycaemic and/or anti-obesity activity BEECHAM GROUP PLC (GB) 1986-02-05 EP disclosed
US-4065576-A OLEIC ACID AND SALTS WEYERHAEUSER COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007090-A1 Process for preparation of (R)-1- (aryloxy)propan-2-ol TOP1, POLN, RIF1 ALDH1A1 180/4885CNR1 3118/4885CNR2 3539/4885
US-20220183279-A1 STABILIZED THIOKETONE FORMULATIONS TXK, KHK, PTMA ALDH1A1 2478/4885CNR1 1566/4885CNR2 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.