Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7110825 | 0.97 | SCN2A (0.56) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| SCHEMBL5427464 | 0.84 | SCN2A (0.56) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| SCHEMBL1794660 | 0.83 | MMP3 (0.65) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| SCHEMBL1605906 | 0.82 | HDAC8 (0.74) | MMP3HDAC8PLK1ALDH1A1KDM4E | |
| SCHEMBL7111671 | 0.82 | SCN2A (0.54) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| SCHEMBL3100592 | 0.81 | MMP3 (0.62) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| SCHEMBL30071626 | 0.81 | MMP3 (0.62) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| Hydrochloric Acid SCHEMBL7110032 | 0.81 | SCN2A (0.53) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| Hydrochloric Acid SCHEMBL7110749 | 0.80 | MMP3 (0.61) | SCN2ASCN5AMMP3HDAC8PLK1 | |
| Guanidine SCHEMBL27689978 | 0.80 | MMP3 (0.61) | SCN2ASCN5AMMP3HDAC8PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600072-B2 | Cardiovascular disorders; antiischemic agents; antiarrhythmia agents | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-29 | — | — | US | claimed |
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | BRENDEL JOACHIM (DE) | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | TNNI3, TNNT2, SCN1B | SCN2A 37/4885SCN5A 50/4885MMP3 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.