Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914178 | 1.00 | CTSV (0.43) | CTSVCTSLADRB3KIF11ADRB1 | |
| SCHEMBL7110854 | 1.00 | CTSV (0.43) | CTSVCTSLADRB3KIF11ADRB1 | |
| SCHEMBL6911748 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6911743 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL7110453 | 0.85 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL7110456 | 0.85 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7967295 | 0.83 | ADRB3 (0.40) | ADRB3ADRB1ADRB2RAB9AMEN1 | |
| SCHEMBL7979049 | 0.83 | ADRB3 (0.40) | ADRB3ADRB1ADRB2RAB9AMEN1 | |
| SCHEMBL7981035 | 0.83 | ADRB3 (0.40) | ADRB3ADRB1ADRB2RAB9AMEN1 | |
| SCHEMBL6905931 | 0.80 | ALOX15 (0.54) | CTSVCTSLADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882707-B1 | NOVEL TRICYCLIC COMPOUNDS AND DRUG COMPOSITIONS CONTAINING THE SAME | ASAHI CHEMICAL IND (JP) | 2003-10-08 | — | — | EP | claimed |
| US-6037362-A | CARBAZOLE DERIVATIVES; DEPROTECTING, AMINATION; ANTILIPEMIC AND ANTIDIABETIC AGENTS; B-ADRENALINE RECEPTOR AGONISTS; DIETETICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-03-14 | — | — | US | claimed |
| EP-0882707-A1 | NOVEL TRICYCLIC COMPOUNDS AND DRUG COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1998-12-09 | — | — | EP | claimed |