SCHEMBL7110889

SCHEMBL7110889

C(=C/c1ccccc1)\CCCOCCC/C=C/c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
HRH3 Q9Y5N1 1/20 0.47
SIGMAR1 Q99720 2/20 0.44
PAM P19021 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HTR2A P28223 3/20 0.41
RELA Q04206 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889742 1.00 IDO1 (0.48) IDO1HRH3SIGMAR1PAMMEN1
SCHEMBL12802434 0.89 HRH3 (0.41) IDO1HRH3SIGMAR1PAMMEN1
SCHEMBL10776843 0.87 TSHR (0.47) IDO1HRH3SIGMAR1HTR2A
SCHEMBL10776841 0.87 TSHR (0.47) IDO1HRH3SIGMAR1HTR2A
SCHEMBL7108904 0.87 IDO1 (0.52) IDO1HRH3SIGMAR1PAMMEN1
SCHEMBL7108908 0.87 IDO1 (0.52) IDO1HRH3SIGMAR1PAMMEN1
SCHEMBL3240089 0.84 IDO1 (0.52) IDO1SIGMAR1PAMHTR2AMAOB
SCHEMBL436426 0.84 IDO1 (0.46) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL8983720 0.84 IDO1 (0.60) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL436427 0.84 IDO1 (0.46) IDO1SIGMAR1PAMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed