SCHEMBL436427

SCHEMBL436427

OOCCCC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
PAM P19021 1/20 0.46
SIGMAR1 Q99720 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PPARA Q07869 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
PPARD Q03181 1/20 0.40
TBXAS1 P24557 1/20 0.40
HTR2A P28223 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436426 1.00 IDO1 (0.46) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL7110889 0.84 IDO1 (0.48) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL10889742 0.84 IDO1 (0.48) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL3240089 0.81 IDO1 (0.52) IDO1PAMSIGMAR1HDAC3HDAC4
SCHEMBL8983720 0.81 IDO1 (0.60) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL8983728 0.81 IDO1 (0.60) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL886961 0.81 IDO1 (0.46) IDO1PAMSIGMAR1MEN1KMT2A
SCHEMBL3795388 0.79 SIGMAR1 (0.50) IDO1PAMSIGMAR1HDAC3HDAC4
SCHEMBL5470587 0.78 PAM (0.50) IDO1PAMSIGMAR1HDAC3HDAC4
SCHEMBL5470592 0.78 PAM (0.50) IDO1PAMSIGMAR1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329704-B1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-08 EP claimed
US-12138323-B2 Initiator system with polymerizable thiourea component, dental composition and use thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-11-12 US claimed
US-20240189196-A1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-06-13 US claimed
EP-4329704-A1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2024-03-06 EP claimed
WO-2022229734-A1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-03 WO claimed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN claimed
EP-2596119-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Advanced Cell Technology, Inc. (US) 2013-05-29 EP claimed
WO-2012012803-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ADVANCED CELL TECHNOLOGY, INC. (US) 2012-01-26 WO claimed
EP-1754465-B1 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2011-10-05 EP claimed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN claimed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US claimed
EP-1754465-A1 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems Heraeus Kulzer GmbH (DE) 2007-02-21 EP claimed
US-4780281-A REDUCTION OF S-PHENYL-4-PENTENYL-HYDROPEROXIDE TO S-PHENYL-4-PENTENOL WAYNE STATE UNIVERSITY (US) 1988-10-25 US claimed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-12545945-B2 Methods for detection of rare subpopulations of cells and highly purified composition of cells ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2026-02-10 US disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed
EP-1754465-A1 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems Heraeus Kulzer GmbH (DE) 2007-02-21 EP disclosed
US-4780281-A REDUCTION OF S-PHENYL-4-PENTENYL-HYDROPEROXIDE TO S-PHENYL-4-PENTENOL WAYNE STATE UNIVERSITY (US) 1988-10-25 US disclosed
US-4780281-A REDUCTION OF S-PHENYL-4-PENTENYL-HYDROPEROXIDE TO S-PHENYL-4-PENTENOL WAYNE STATE UNIVERSITY (US) 1988-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 IDO1 4649/4885PAM 1789/4885SIGMAR1 1761/4885
US-12545945-B2 Methods for detection of rare subpopulations of cells and highly purified composition of cells ALDH1A2, EYA3, EYA2 IDO1 4604/4885PAM 4754/4885SIGMAR1 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.