Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 18/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 17/20 | 0.71 |
| ▸ | PTPN2 | P17706 | 16/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 10/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 10/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105169 | 0.84 | PTPN5 (0.70) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL24155564 | 0.80 | NPC1 (0.67) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL31170 | 0.79 | NPC1 (0.81) | PTPN5PTPN1PTPN2MEN1MAPT | |
| Methane SCHEMBL29265168 | 0.78 | NPC1 (0.79) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL31476 | 0.78 | NPC1 (0.79) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL1660542 | 0.77 | NPC1 (0.67) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL20656686 | 0.77 | BCHE (0.66) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL24295077 | 0.77 | PTPN1 (0.63) | PTPN5PTPN1PTPN2MEN1MAPT | |
| SCHEMBL2247579 | 0.77 | RAB9A (1.00) | MEN1MAPTHPGDKMT2AHSD17B10 | |
| SCHEMBL29919334 | 0.76 | NPC1 (0.71) | MEN1MAPTHPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812319-B9 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2003-10-08 | — | — | EP | claimed |
| EP-0812319-B1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2002-07-10 | — | — | EP | claimed |