Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112014 | 1.00 | NFE2L2 (0.46) | NFE2L2FBP1P4HBPHGDHCTSC | |
| SCHEMBL4085102 | 0.78 | NPC1 (0.54) | MEN1LMNAKMT2AMAPTPKM | |
| SCHEMBL4085100 | 0.78 | NPC1 (0.54) | MEN1LMNAKMT2AMAPTPKM | |
| SCHEMBL715978 | 0.75 | NFE2L2 (0.49) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL715979 | 0.75 | NFE2L2 (0.49) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL4656669 | 0.72 | CTSC (0.65) | CTSCMEN1LMNAKMT2AMAPT | |
| SCHEMBL30128849 | 0.72 | CTSC (0.65) | CTSCMEN1LMNAKMT2AMAPT | |
| SCHEMBL3904046 | 0.71 | NFE2L2 (0.73) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL5496405 | 0.71 | NFE2L2 (0.73) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL13763536 | 0.71 | NPC1 (0.59) | MEN1KMT2AMAPTPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443926-A1 | PYRIDINE DERIVATIVES AS NMDA-RECEPTOR SUBTYPE BLOCKERS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037333-A1 | PYRIDINE DERIVATIVES AS NMDA-RECEPTOR SUBTYPE BLOCKERS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-08 | — | — | WO | disclosed |