Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1950583 | 0.94 | — | — | |
| Bicarbonate SCHEMBL19128 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2707848 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1115606 | 0.89 | — | — | |
| Bicarbonate SCHEMBL6946373 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15283203 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL11375032 | 0.88 | — | — | |
| Bicarbonate SCHEMBL301926 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17685557 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7021729 | 0.88 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115256892-A | Preparation method of degradable high-barrier composite BOPP (biaxially-oriented Polypropylene) matt film | 启明新材料股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115228428-A | High-entropy magnesium-aluminum carbonate hydrotalcite compound doped with elements with different valence states, and preparation method and application thereof | 青海大学 | 2022-10-25 | — | — | CN | claimed |
| CN-112759324-A | High-strength concrete and preparation process thereof | 云南永吉福商品混凝土有限公司 | 2021-05-07 | — | — | CN | claimed |
| US-10988659-B2 | Layered double hydroxides for oil-based drilling fluids | SAUDI ARABIAN OIL COMPANY (SA) | 2021-04-27 | — | — | US | claimed |
| CN-112657470-A | Method for modifying hydrotalcite by using long carbon chain anionic surfactant | 乌日娜 | 2021-04-16 | — | — | CN | claimed |
| CN-111543695-A | Antibacterial mask and preparation method thereof | 上海工程技术大学 | 2020-08-18 | — | — | CN | claimed |
| CN-111448286-A | Layered double hydroxide for oil-based drilling fluids | 沙特阿拉伯石油公司 | 2020-07-24 | — | — | CN | claimed |
| CN-107416872-B | Preparation method of magnesium-aluminum carbonate hydrotalcite | 上海华峰新材料研发科技有限公司 | 2020-07-24 | — | — | CN | claimed |
| EP-3668944-A1 | LAYERED DOUBLE HYDROXIDES FOR OIL-BASED DRILLING FLUIDS | Saudi Arabian Oil Company (SA) | 2020-06-24 | — | — | EP | claimed |
| CN-108706620-B | Nano calcium hydroxide/magnesium aluminum carbonate nano hydrotalcite nano composite material and preparation method thereof | 西北工业大学 | 2020-06-16 | — | — | CN | claimed |
| CN-111087215-A | High-strength anti-crack concrete and preparation process thereof | 杭州三中新型建材科技有限公司 | 2020-05-01 | — | — | CN | claimed |
| CN-110667220-A | Packaging winding film and preparation method thereof | 宁波鸿雁包装材料有限公司 | 2020-01-10 | — | — | CN | claimed |
| US-20190055450-A1 | LAYERED DOUBLE HYDROXIDES FOR OIL-BASED DRILLING FLUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2019-02-21 | — | — | US | claimed |
| WO-2019036261-A1 | LAYERED DOUBLE HYDROXIDES FOR OIL-BASED DRILLING FLUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2019-02-21 | — | — | WO | claimed |
| CN-121271111-A | Oil-resistant chemical-corrosion-resistant PVC sheath, cable and preparation method thereof | 浙江宏策电缆有限公司 | 2026-01-06 | — | — | CN | disclosed |
| CN-116178788-B | Method for preparing hydrotalcite-containing nano flame retardant by using blast furnace dust and chromium-containing aluminum mud | 中国消防救援学院 | 2024-08-20 | — | — | CN | disclosed |
| CN-116178788-B | Method for preparing hydrotalcite-containing nano flame retardant by using blast furnace dust and chromium-containing aluminum mud | 中国消防救援学院 | 2024-08-20 | — | — | CN | disclosed |
| EP-0640387-A1 | Preparation of isophorone using a magnesium/aluminum mixed oxide catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5286785-A | Heat resistance | DSM N.V. (NL) | 1994-02-15 | — | — | US | disclosed |
| EP-0520568-A2 | Thermostable ethylene-carbon monoxide copolymer | DSM N.V. (NL) | 1992-12-30 | — | — | EP | disclosed |